Más allá de la articulación: soluciones interdisciplinarias para mejorar la atención al paciente con TGCT

 

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Beyond the Joint: Cross-Specialty Solutions for Advancing TGCT Patient Care

 

Parent Summary (160 characters) 

 

Explore TGCT recognition, clinical evidence, treatment strategies, and management of adverse events with CSF1R inhibitors in an interdisciplinary context.

 

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This online CME activity addresses interdisciplinary strategies for improving outcomes in patients with tenosynovial giant cell tumor (TGCT). Faculty review the disease spectrum, including diffuse and localized subtypes, and highlight clinical features that warrant early referral to specialists. The program examines evidence from clinical trials of CSF1R inhibitors, with a focus on functional endpoints and patient-reported outcomes that capture the real-world impact of therapy on mobility, pain, and quality of life. Participants will learn how to apply trial findings to select appropriate treatment approaches tailored to disease burden and functional impairment. The session also emphasizes proactive management of adverse events associated with systemic therapy, including monitoring, early intervention, and supportive care strategies to maintain safety and adherence.

 

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Video # 1

Title: The Tumor That’s Not So Tiny: Understanding the Impact of TGCT

Summary: Review TGCT epidemiology, subtypes, diagnosis, and patient burden, with emphasis on avoiding misdiagnosis and improving referral pathways.

Video # 2

Episode Title: Beyond the Scalpel: When TGCT Surgery Isn’t the Solution

 

Episode Summary (160 characters): Explore the limitations of surgery for diffuse TGCT, recurrence risks, and when to transition to systemic therapy to preserve function and quality of life.

Video # 3

Title: Unlocking the CSF1R Code: Targeted Pathways and Tailored Choices

Summary: Explore the biological role of the CSF1/CSF1R pathway in TGCT pathogenesis and review targeted approaches with CSF1R inhibitors, including key emerging agents.

Video # 4

Episode Title: Clinical Evidence in Focus: Interpreting Data on Systemic Therapy Targeting CSF1R

 

Episode Summary (160 characters): Review clinical data on a first-in-class CSF1R-targeted tyrosine kinase inhibitor in TGCT, including efficacy and safety outcomes as well as unmet needs. 

 

Video # 5

Episode Title: Surgical Crossroads: Practical Considerations for Optimizing Treatment in TGCT

 

Episode Summary (160 characters): Drs. Gelderblom and van de Sande discuss managing recurrent diffuse TGCT, weighing surgical limits, referral pathways, and systemic therapy options.

 

Video # 6

Episode Title: Emerging Evidence in Focus: Interpreting Data on Next-Generation CSF1R TKIs

 

Episode Summary (160 characters): Dr. Hans Gelderblom reviews emerging data from the MOTION and MANEUVER trials of next-generation CSF1R TKIs in TGCT, highlighting efficacy and safety outcomes. 

 

Video # 7

Episode Title: Applying the Evidence: TGCT Treatment Insights for Sports Medicine Physicians

 

Episode Summary (160 characters): Dr. Gelderblom and Dr. Cole discuss timely recognition of TGCT in sports medicine, referral pathways, and systemic therapy selection with CSF1R TKIs.

 

Video # 8

Episode Title: The Safety Equation: Managing Adverse Events Associated With CSF1R Inhibitors in TGCT

 

Episode Summary (160 characters): Dr. Hans Gelderblom reviews safety profiles of CSF1R inhibitors in TGCT and shares practical strategies for monitoring and managing adverse events.

 

Video # 9

Episode Title: Patient Perspective: Navigating TGCT Treatment—Surgery vs Systemic Therapy

 

Episode Summary (160 characters): Hear a patient–physician dialogue on TGCT diagnosis, impact on mobility, treatment journey, and how treatment choices affect daily function and quality of life.

 

Video # 10

Episode Title: All Sides of the Joint: Integrated TGCT Care Across Specialties

 

Episode Summary (160 characters): Experts discuss multidisciplinary TGCT care across specialties, emphasizing early diagnosis, timely referral, treatment selection, and shared decision-making.